The freeze dryer consists of a refrigeration system, a vacuum system, a heating system, and an electrical instrument control system. The main components are drying ovens, condensers, refrigeration units, vacuum pumps, heating/cooling devices, etc. Freeze-drying (hereinafter referred to as lyophilization) is a method in which an aqueous substance is first frozen into a solid state, and then the water therein is sublimated from a solid state into a gaseous state to remove water and preserve the substance. Principle and Advantages of Freeze Dryer Principles and Advantages of Freeze Dryer We know that the freeze-drying principle of freeze dryer is: freeze-drying is a technique of drying by the principle of sublimation, which is to freeze the dried material at low temperature and then in a proper vacuum environment. So that the frozen water molecules are directly sublimated into a process in which water vapor escapes. The product obtained by freeze drying is called a lyophilizer. This process is called lyophilization. The substance is always in a low temperature (freezing state) before drying, and the ice crystals are uniformly distributed in the substance, and the sublimation process does not cause concentration due to dehydration, thereby avoiding side effects such as foaming and oxidation caused by water vapor. The dry matter is dry and the porous volume of the sponge is almost constant and is very soluble in water and restored to its original state. Physical and biological denaturation of dry matter is prevented to the greatest extent. So what are the benefits of freeze drying? Let's take a look: one. Freeze drying is carried out at low temperatures and is therefore particularly suitable for many heat sensitive materials. Such as protein, microorganisms and the like will not degenerate or lose biological vitality. Therefore, it is widely used in medicine. two. Since the drying is carried out in a frozen state, the volume is almost constant, and the original structure is prevented from being concentrated. three. After drying, the porous material is porous and spongy. After adding water, it dissolves quickly and completely restores the original trait almost immediately. four. Since the drying is carried out under vacuum, there is very little oxygen, so some easily oxidizable substances are protected. Seven. Drying can eliminate more than 95-99% of water so that the dried product can be preserved for a long time without deterioration. Therefore, freeze-drying of freeze dryers is currently widely used in scientific research and other sectors of the pharmaceutical industry. Application field of freeze dryer Freeze-drying is a method of pre-freezing an aqueous material and then sublimating it under vacuum to obtain a dried article. The freeze-dried items have the same biological and chemical properties, and are easy to store for a long time. After adding water, they can be restored to the form before lyophilization, and can maintain their original biochemical characteristics. Therefore, freeze-drying technology is widely used in the chemical industry, biological products and other fields. Before lyophilizing with a lyophilizer, the items to be dried are placed in a low-temperature refrigerator or liquid nitrogen, and the contents are completely frozen in ice before being freeze-dried. The lyophilizer main unit and the vacuum pump are connected by a vacuum tube, and the joint is made of an international standard clamp. The clamp contains a sealing rubber ring. Before connecting, apply a proper amount of vacuum grease on the rubber ring and then clamp it with a clamp. The power supply socket of the vacuum pump is installed on the right side of the main unit, and the power line of the vacuum pump is connected. Check the vacuum pump to confirm that the vacuum pump oil has been filled and that it is not oil-free. The oil level must not be lower than the center line of the oil mirror. Please read the instruction manual of the vacuum pump before using it for the first time. The “O†type sealing rubber ring above the main cold trap should be cleaned. When using it for the first time, apply a thin layer of vacuum grease. Place the plexiglass cover on the rubber ring and gently rotate it a few times to facilitate sealing. . Freeze dryers have a wide range of applications in the pharmaceutical, biological, chemical and food industries. Freeze-drying techniques are very suitable for heat sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues. Concerned about surprises Label: Introduction to the principle, advantages and application areas of freeze dryer Previous: Viewing the performance of the refrigeration system from the temperature change of the compression condensing unit Next: General principles of pressure transmitter application Mechanical Diaphragm Metering Pump
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Fives. The loss of some volatile components in the material when dried at low temperatures is small for some chemical products and foods to dry.
six. The growth of the microorganisms and the action of the enzyme during the freeze-drying process cannot be performed and thus the original sexual appearance can be maintained. 