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Fluorescent nanodiamond particles in the EU Dinamo project
"In the past, the test method only allowed the detection of intracellular biomolecules for a short period of time. The focus of the technical research was on how to replace the fluorescent biomolecular dyes used for cold light labeling in cancer cell research," Nesladek added.
The latest NDPs technology has unparalleled advantages: high biocompatibility, long time in cells and no influence on cell mechanism; more importantly, these nanodiamonds are controllable, and some optical, magnetic and artificial designs can be made. Surface properties. NDPs enter the cell membrane at their nanometer size, and this ultra-non-invasive permeation mode has no effect on cell function, and is almost zero damage to cells. The luminescence and magnetism of NDPs change depending on their interaction with the intracellular environment.
The surface of NDPs has properties attached to specific biomolecules, such as DNA molecules. When scientists transport these biomolecule-attached nanodiamonds to target cells, NDPs can collect, detect, or alter the biological components of the cells. In this way, fluorescent nanodiamond can not only detect cell changes in the early stage of cancer, but also perform preliminary correction treatment on these cancer cells. Subsequent research projects will be implemented in the EU's DIAMANT project.
Some scientists are very optimistic about this application of fluorescent nanodiamonds. "The development of drug delivery carrier technology plays an important role in the treatment of many diseases, including cancer and other difficult diseases," said Fedor Jelezko of the Institute of Quantum Optics at Ulm University in Germany. Said, "The Dinamo project in the European Union is an innovative attempt and breakthrough in the use of nano-diamond materials in the medical field of drug delivery technology." With the help of fluorescence microscopy, the nanodiamond particles carrying the drug are clearly observed due to their special optical properties, which provides great convenience for the accurate delivery and delivery of intracellular drugs. At present, the demonstration of NDPs detection technology has been carried out at the Gustav Roussie Cancer Institute in France and the Paris Teachers College (ENS).
There are also some experts who are cautious about the technology. François Treussart, a professor of physics at ENS, argues: “Diamond is a relatively inert substance that cannot be degraded in the human body and has the risk of being out of the body; Although many experiments have now demonstrated that diamond can carry drugs for intracellular delivery, this is limited to cell assays and mice in culture dishes, and the unknowns and risks of human trials are still unknown.
However, François Treussart added that although the Dinamo project in the EU has unknown risks, nanodiamonds, as diagnostic equipment and testing tools, are still promising in medical applications, especially in the field of regenerative medicine. And tracking. Recently, the Fluorescence-ND project team of the Institute of Atomic and Biomolecular Sciences of the Central Research Institute of Taiwan has studied this subject.
In targeted cells, fluorescent nanodiamond probes are used to detect and transmit changes in the mechanisms that occur within cancerous cells. At present, the theoretical research of the Dinamo project has come to an end, and the University of Stuttgart in Germany has begun to develop such NDPs probes. In addition, the scientists found that the Dinamo project is very accurate and effective for the diagnosis of breast and colorectal cancer, but not for other cancers, and even not diagnosed. Nesladek said that many questions will drive the EU's research and development efforts in the next phase of the project. (Compiled from "Nanodiamonds: A cancer patient's best friend")
Space-Saving Design: These toilets mount to the wall, saving valuable bathroom floor space. This is especially practical for smaller bathrooms or if you prefer a more minimalist aesthetic.
Heated toilet seat: A cold toilet seat can be uncomfortable, especially during the colder months. Wall-mounted smart toilets usually come with a heated seat that can be adjusted to your preferred temperature for a comfortable experience.
Adjustable water temperature and pressure: These toilets often offer adjustable water temperature and pressure settings for the bidet function, which allows users to customize their cleaning experience to their liking.
Warm air drying: After using the bidet function, wall-mounted smart toilets often provide a warm air drying option. This eliminates the need for toilet paper and promotes a more hygienic and environmentally friendly method.
Additional features: Some wall-mounted smart toilets may include additional features such as built-in air purifiers, deodorizers, night lights, and even background music or Bluetooth connectivity.
Abstract The European Union recently announced a research project called Dinamo to create a non-invasive nanotechnology sensing platform for real-time monitoring of biomolecules in cancer cells. The protagonist of this technology project is the long-awaited nano-diamond. &n
The European Union recently announced a research project called Dinamo to create a non-invasive nanotechnology sensing platform for real-time monitoring of biomolecules in cancer cells. The protagonist of this technology project is the long-awaited nano-diamond.